Abstract: Sarcopenia is a syndrome characterized by progressive and generalized loss of skeletal muscle mass, strength and function. End-stage renal disease (ESRD) patients are at a higher risk of accelerated muscle wasting due to the renal diseases itself, various complications, dialysis treatment and reduced activity from dialysis treatment. The incidence of sarcopenia is higher in dialysis patients and the mortality will be increased in dialysis patients with sarcopenia, highlighting the great importance of early prevention, detection and treatment of muscle wasting. In this article, we summarize the pathogenesis, diagnosis and treatment of sarcopenia in ESRD patients on maintenance dialysis.

Key words: nd stage renal disease, Dialysis, Sarcopenia, Pathogenesis, Diagnosis and treatment