Abstract: Objective  To investigate the status quo and influencing factors of health-promoting lifestyle in maintenance hemodialysis (MHD) patients, and to explore its correlation with e-health literacy.  Methods  A total of 141 patients with MHD in the Hemodialysis Center, West China Hospital of Sichuan University from February 2022 to May 2022 were selected as the research subjects. A general information questionnaire, eHealth Literacy Scale (eHEALs), and Revised Health Promoting Lifestyle Profile-Ⅱ (HPLP-ⅡR) were used to conduct a questionnaire survey for the MHD patients.  Results   The score of health promotion lifestyle was 104.00±15.01 points, and the score of e-health literacy was 25.26±8.91 in the MHD patients. Multivariate linear regression showed that educational level (high school diploma β=0.285, P=0.030; university degree or above β=0.388, P=0.003), and e-health literacy (β=0.365, P＜0.001) were the main influencing factors for health promotion lifestyle. Spearman correlation analysis showed a positive correlation between health literacy and health promotion lifestyle (r=0.474, P＜0.001).  Conclusion  The health promotion lifestyle was better, and e-health literacy was in a general level in the MHD patients. There was a positive correlation between health promotion lifestyle and e-health literacy. We should take targeted measures to improve the e-health literacy and healthy lifestyle to promote the quality of life in MHD patients.

Key words: Maintenance hemodialysis, Health promoting lifestyle, Electronic health literacy, Chronic kidney disease