Abstract: Parathyroidectomy can effectively treat the secondary hyperparathyroidism (SHPT). However, complete resection of the parathyroid glands during operation is often impossible due to the anatomical and physiological characteristics of parathyroid glands. Thereby the risk of short-term or long-term recurrence increases. Intraoperative parathyroid hormone (ioPTH) determination has been proven to be of great value in improving effectiveness and safety of the surgery and in reducing the recurrence and complications after the surgery. However, there is no consensus on determination standard. This paper aims to review the research progresses and current status of ioPTH during parathyroidectomy surgery for SHPT and to provide more theoretical bases and research targets for SHPT surgery.

Key words: Intraoperative parathyroid hormone, Secondary hyperparathyroidism, Parathyroidectomy