Abstract: Objective  To systematically evaluate and integrate the qualitative studies on fatigue experience and management in hemodialysis patients.  Methods   Cochrane Library, Web of Science, PubMed, CINAHL, Embase, Scopus, CBM, CNKI, Wanfang, and VIP databases were searched for qualitative studies on the experience and management of fatigue in hemodialysis patients from their inception to December 2023.  Results  A total of 9 articles were included, 38 results were extracted, 10 categories were formed, and 4 integrated results were summarized: hemodialysis patients' cognition of fatigue, the impact of fatigue, patient self-management strategies, fatigue management needs and challenges.   Conclusion  There are obstacles in the management of fatigue in hemodialysis patients, such as cognitive deficiency, negative emotional influence, incomplete self-management strategies, and imprecise interventions. Medical institutions should build diversified management strategies and provide comprehensive support to improve self-management strategies, survival cycle, and quality of life in hemodialysis patients.

Key words: Hemodialysis; , Fatigue; , Experience; , Management; , Qualitative research