Abstract: Objective  To evaluate and summarize the best evidence for the management of thirst symptoms in hemodialysis patients, and to provide evidence-based data for clinical practice.  Method  We systematically searched domestic and foreign computerized decision support systems, guideline websites, databases, and websites of professional associations relating to the management of thirst symptoms in hemodialysis patients from establishment of the databases to November 2023. AGREE II, JBI  and CASE evaluation tools were used to evaluate the quality of the included literature and to summarize the evidence of the literature that meets the requirements.  Result  A total of 12 articles were included, including one guideline, one evidence summary, 3 systematic reviews, and 7 randomized controlled trials.   Conclusion  This study summarizes the best evidence for the management of thirst symptoms in hemodialysis patients and provides a scientific basis of clinical practice for healthcare professionals.

Key words: Hemodialysis, Thirst, Summary of evidence, Evidence-based nursing