Chinese Journal of Blood Purification

Chinese Journal of Blood Purification ›› 2024, Vol. 23 ›› Issue (11): 878-880.doi: 10.3969/j.issn.1671-4091.2024.11.016

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Leukemia patients with severe iron overload and treated with double filtration plasmapheresis: report of two cases and review of the literature

SONG Yi-Fan, CHEN Li-ting, ZHANG Chao, REN Ye-ping, WANG Qin   

  1. Department of Nephrology, Shenzhen University General Hospital, Shenzhen 518055, China
  • Received:2024-06-04 Revised:2024-09-05 Online:2024-11-12 Published:2024-11-12
  • Contact: 518055 深圳，1深圳大学总医院肾脏病科 E-mail:wangqinmail@vip.163.com

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Abstract: We report two leukemia patients with severe iron overload and successfully treated with double filtration plasmapheresis (DFPP). After the treatment, serum ferritin reduced significantly without any severe complications. We suggest that DFPP is a fast and efficient therapy to remove ferritin, and can be used in severe iron overload patients with poor response or intolerance to drug treatment. 

Key words: Double filtration plasmapheresis, Iron overload, Leukemia

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