Abstract: Objective  The prognostic factors of dialysis vintage in patients on maintenance peritoneal dialysis were analyzed.  Methods  The clinical data of 571 patients on maintenance peritoneal dialysis (PD) in Evergreen Tree Nephrology Association (ETNA) Peritoneal dialysis database from November 2005 to May 2020 were analyzed retrospectively. The survival rate and technical survival rate were calculated, and the risk factors influencing prognosis were analyzed. PD patients were divided into long dialysis vintage group (≥60 months) and short dialysis vintage group (<60 months), and the prognosis of the patients in different dialysis vintage groups and the risk factors affecting dialysis vintage were analyzed.  Results  The 1-,2-,3-,5- and 10- year cumulative survival rates of the 571 PD patients were 94%, 88.8%, 80.9%,70.3% and 49.8%. The cumulative technical survival rates were 94%, 88.8%,80.8%,69.3% and 39.2%, respectively. COX Multivariate regression analysis showed that chronic obstructive pulmonary disease (COPD) history (HR=3.39, 95% CI: 1.054～10.576, P=0.040), elevated Low-Density lipoprotein cholesterol (LDL-c) (HR=1.222, 95% CI: 1.032～1.447, P=0.020) and pulmonary infection (HR=1.568, 95% CI: 1.252～1.965, P＜0.001) were independent risk factors of death in PD patients (P＜0.05). Logistic regression analysis showed that Smoking (OR=0.349，95% CI: 0.139～0.873，P=0.024), elevated intact parathyroid hormone(iPTH) (OR=0.999, 95% CI: 0.998～1.000, P=0.048)and low urine volume (OR=1.001, 95% CI: 1.000～1.001, P＜0.001) were independent risk factors of technical failure.  Conclusion  Smoking, elevated iPTH and low urine volume are independent risk factors of technical failure. Smoking cessation, rational reduction of iPTH and protection of residual renal function can prolong patients' dialysis vintage.

Key words: Peritoneal dialysis, Survival analysis, Technical survival rate, Risk factors, Dialysis vintage