Abstract: Hemodialysis (HD) is one of the most commonly used blood purification techniques for critically ill patients, but it will inevitably lead to many complications due to various factors. Among them, complications related to arteriovenous fistula (AVF) are one of the important causes for treatment failure and death in HD patients. Some studies have found that persistently positive antiphospholipid antibody (aPL) is commonly present in HD patients, which may be involved in the AVF-related complications. This paper summarizes the current research progress of aPL in AVF-related complications in HD patients, in order to improve the prognosis of HD patients with AVF-related complications and to provide bases for the prevention, monitoring and treatment of the complications.

Key words: Antiphospholipid antibody, Hemodialysis, Arteriovenous fistula, Complication