Abstract: Objective To review the research status, evaluation tools, and influencing factors of post-dialysis fatigue in maintenance hemodialysis (MHD) patients, aiming to provide references for clinical workers to improve their prognosis and quality of life.  Methods  We searched the databases of PubMed, Web of science, Cochrane library, Science Direct, Embase, CINAHL, CNKI, Wanfang, VIP and SinoMed for post-dialysis fatigue in MHD patients from inception to September 2024.  Results  A total of 22 articles were included. The commonly used evaluation tool was the open-ended assessment questionnaire for post-dialysis fatigue. The incidence and severity of post-dialysis fatigue were different among the research series. The main influencing factors included sociodemographic factors, dialysis related factors, disease-related factors, physical factors, and psychological factors.  Conclusions  The incidence of post-dialysis fatigue is high in MHD patients. Various tools were available for the assessment of post-dialysis fatigue, but multidimensional and specific assessment tools are yet absent. A diverse of influencing factors are present for the post-dialysis fatigue in MHD patients.

Key words: Maintenance hemodialysis, Post-dialysis fatigue, Research status, Assessment tool, Influencing factor