The Double Plasma Molecular Adsorption System (DPMAS) is a commonly used blood purification technique for treating severe liver diseases, with nurses playing a dominant role in its implementation. Therefore, the standardization and professionalism of nursing procedures are crucial for ensuring treatment safety. Currently, clinical nursing practice is characterized by inconsistent operational standards, inadequate implementation of procedural details, and improper use of equipment and consumables, which may affect treatment efficacy. To standardize nursing procedures and improve nursing quality, the Blood Purification Nursing Professional Committee of the Chinese Nursing Association organized experts from relevant fields to develop the Expert Consensus on Nursing Procedures for the Double Plasma Molecular Adsorption System (2026 Edition) based on domestic and international literature and clinical experience, with a focus on the standardization, practicality, and feasibility of nursing procedures. This Consensus aims to promote the standardized and consistent implementation of DPMAS procedures, thereby enhancing the safety and stability of the treatment process and providing more reliable and controllable blood purification support for patients with severe liver diseases.