Abstract
【Abstract】Objective To study the effect of urokinase on thrombosis of the arteriovenous fistulas by peripheral artery infusion and intraarterial infusion. Methods 12 patients with thrombosis of the angioaccess were infused urokinase via a small needle into the feeding artery, 4 patients were performed intra-arterial urokinase infusion into artery extrimity of the thrombus at DSA unit. The dosage of urokinase was 750,000～1,000,000IU, and the infusion time was average 3～4 hours. Result A complete thrombolysis with return of bruit and thrill was obtained in 50% patients by peripheral artery infusion and 75% patients by intra-arterial infusion. In follow-up 6～44 months,there are good patency in all the successful case after thrombolysis except of one case reclotted. conclusion Urokinase local infusion provides a useful means of preservation on arteriovenous fistula and may be used as the therapy of first choice in dialysis patients.
Key words
Urokinase /
Intra-arterial infusion /
Haemodialysis patients /
Digital subtraction anglography
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