【Abstract】Objective We study and report a new operation method of internal arteriovenous fistula,and it is a simple, fast and safe method. Methods 90 CRF patients were treated with hemodialysis. We divided the patients into three groups. There were 30 patients in every group. In A group, the internal arteriovenous fistula were performed operation with new method. In B group, the internal arteriovenous fistula conneted with titamiu ring nail. In C group, the artery extremity and vein extremity were connected with stitch method. We used internal arteriovenous fistula for hemodailysis four weeks after operation. The blood flux of them, the occuring rate of thrombus, angiomatous and the time of operation were observed. Rasults The internal arteriovenous fistula mature time and the blood flux were samed in three groups. In A group, the operation time was shorter than other group (P<0.01)， the occuring rate of thrombus is lower than other groups （P<0.01). There were not any angiomatous in A group. Conclusion The new skill method is simple, fast and safe. There were not any eyewinke and stenosis at arteriovenous connecting.