【Abstract】Objective To use intermittent hemodialysis (IHD)to treat multiple organ dysfunction syndrome(MODS), observe it's clinic practice and effect. So as to observe if it can be instead of continuous renal replacement therapy (CRRT) to treat MODS. Methods Use IHD to treat MODS 6 cases, observe the clinic treatment effects of renal function ,body's condition and other complications. Compare with CRRT. Results Using IHD to treat MODS , blood purification was selected as early as possible , and treat the primary disease, protect kidney function ,gradually correctitude water and electrolyte unbalance, it will be a good result. Conclusion Using IHD to treat MODS can get good result as using CRRT.