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Chinese Journal of Blood Purification ›› 2003, Vol. 2 ›› Issue (1) : 17-19.

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Abstract

【Abstract】Objective To observe the mechanism of chronic renal failure related with serum leptin levels. Methods Serum leptin levels of chronic renal failure were determined by isotopic radioimmunoassay. Serum creatine, hemoglobin were determined by biochemical measurements. Results Compared with the control group and normal renal function group , serum leptin levels was higher in non-dialysis and dialysis uremia patients. There were nagtive relationship between leptin and hemoglobin .There are no significant in non-dialysis and dialysis uremia patients. Serum leptin levels are no related with Alb, TG, LDL, HDL. Conclusion Serum leptin levels are higher in the uremia non-dialysis patients and the dialysed patients. Primary dialysis may not able to clean leptin from blood.