Objective TO evaluate the efficacy of artifical liver on patients with severe hepatitis patients. Methods seventeen severe hepatitis patients were treated with KM8800 plasma exchange system for 31 times. The serum total bilirubin (TBIL), alanine aminotransferase(ALT), platelet(PLT) and prothrombin time(PT) were meosured before and after the treatment. Results There were significant differences of TBil(P<0.001) and PT(P<0.005) levels between before and after treatment. There were no significant difference of ALT and PLT. Conclusion Artificial liver treatment can improve the biochemistry indexes of patients suffering from severe hepatitis and is berefit for the regeneration of liver cells. It is a valuable supporting treatment for svere hepatitis.
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