【Abstract】Objective To investigate the changes of the early glycation products(fructosamine) and the advanced glycation end products(AGEs) in the patients on peritoneal dialysis.And to study the relationship between the glycation and peritoneal dialysis. Methods Levels of fructosamine was measured by nitroblue tetrazolium method.And levels of AGEs were measured by fluorescence method. Results Levels of patients on CAPD were significantly higher as compared with those in control subjects (P<0.01). And levels of peritoneal dialysis fluid AGEs were different on 0h, 2h, 4h (P<0.01).Conclusion It is shown that fructosamine and AGEs were significantly higher in patients on CAPD,and they could not be effectively removed by peritoneal dialysis.They could also reduce peritoneal transport effect.