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Chinese Journal of Blood Purification ›› 2003, Vol. 2 ›› Issue (6) : 301-304.

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Abstract

Objective This study is designed to observe the effects of cool dialysate on decreasing episodes of dialysis-related hypotension. Methods Using self-across method, cool dialysate (35.5℃, group C) and traditional dialysate (37℃, group T) were used for 8～10 dialysis sessions respectively in every 15 hypotension-prone patients. RBV (rdative blood volume, arterial-tube temperature which reflects patient's core temperature, blood pressure, heart rate, ultrafiltration rate and the occurrence of hypotension were observed at every 60-min intervals. Results There are 151 hemodialysis sessions in group C in total and 149 hemodialysis sessions in group T. RBV in both groups decreased gradually during hemodialysis sessions. When hypotension occurred, the average RBV was 78% in group C and 80% in group T. Compared to group T, the eposidic hypotension rate in group C was lower (25.2% vs 39.6%, P=0.002); episodic time was delayed (3.93±0.49 vs 3.66±0.73 hours, P=0.038); ultrafiltration volume increased when hypetension occured (3500.21±843.10ml，3157.28±729.50ml，P=0.035). There were no difference between two groups in RBV and heart rate. Core temperatures increased during hemodialysis, especially in group T. Conclusion Cool dialysate can reduce the episodes of hypotension through decreasing core -temperature changes.