Abstract
Objective and Metheds The standard CRRT instrument is too expensive for some small hospitals to afford for severe patients. hence From 1995, we used common dialysis machine to design a bedside blood purification device.
Results Until now we have used it to treat 123 patients with chronic or acute renal failure caused by any kinds of diseases. We performed 643 episodes of treatment, including IHD intermittent hemodialysis (203 patient times), HDF hemodiafiltration(107 patient times), HP hemoperfusion or HP plus HD hemodialysis (45 patient times), SUF single ultrafiltration (28 patient times) and CVVHDF continuous venorenous hemodiafiltration (146 patient times) and CVVH continuous venovenous hemofittration (114 patient time). Every treatment episode continued 4～22 hours (mean value 7.8hours), blood flow was about 60～250ml/dl, dialysate flow was about 500～800ml/l. In our experience, we can use this device to decrease BUN or SCr to 50～85% and it can also decrease inflammatory mediator such as TNF, IL-6 or CRF to 43～63% in one treatment episode. Conclusion This device is safe and it is easy to perform in clinical practice. And it can increase the survival rate of MOF, CRF and ARF patients in ICU just as CRRT does.
Key words
Bedside dialysis machine
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