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Chinese Journal of Blood Purification ›› 2003, Vol. 2 ›› Issue (8) : 416-418.

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Abstract

objective To analyze the reason and risk factors associated with dropout of patients within one year after initiation of continuous ambulatory peritoneal dialysis (CAPD). Methods Between 1st April 2000 and 31st March 2003, all new CAPD patients were recruited. Patient demographic characteristics, duration of dialysis, the prevalence of diabetes, date and cause of dropout, cause of death were recorded. Comorbidity at initiation of dialysis was assessed by Charlson index and physical injury index. Results A total of 139 patients were included in this study, of which 50 (35.97%) cases dropped out. Among the 40 cases who dropped out within one year after initiation of CAPD, 32cases died (6died of acute myocardial infarction, 7died of congestive heart failure, 3died of stroke, 5 died of infection, 3died of rejecting treatment, 1 died of multiple system organ failure, 2 died of malignancy, 2 died of respiration failure, 3 died of others), 4 cases received renal transplantation, 4 cases were switched to hemodialysis. The relative risk (RR) of death established by logistic regression analysis for effect of comorbidity assessed by Charlson index and physical injury index, gender on patients dropping out within one year after initiation of CAPD were as follows: Charlson index, RR = 1.554 ( P = 0.004); physical injury index, RR = 2.125 (P = 0.037); gender, RR=2.821 (P=0.034). Conclusions Our study suggests that cardiovascular event is the primary cause of death in patients who dropped out within one year after initiation of CAPD, and comorbidity is an important risk factor for the dropout.