Abstract
Objective To observe the influence on serum electrolyte in the treatment of chronic severe hepatitis with continuous hemodiafiltration(CHDF) plus plasma exchange(PE). Methods Fifty-five patients with chronic severe hepatitis were selected randomly, 21cases of them complicated with hypokalemia, 20 cases complicated with hyponatremia, 27 cases complicated with hypochloraemia. All patients were treated with PE and CHDF with an artificial liver support system of KM-880 and JUN-500 on the basis of general treatment before and after the treatment, the serum levels of electrolyte including K+、Na+、Cl-、HCO3-、Ca+ + were compared. Results The patients' serum levels of electrolyte K+、Na+、Cl- showed significant difference after the treatment (P<0.05）, but the serum levels of electrolyte HCO3- 、Ca+ +、have a different result（P>0.05）. Conclusion CHDF plus PE can effectively rectify the disturbance of electrolyte and keep the balance of internal environment of the patients with chronic severe hepatitis.
Key words
Plasma exchange /
Severe hepatitis /
Electrolytes
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