Objective To evaluate the outcome of continuous renal relacement therapy (CRRT) on treating serious infection occured to pationts after kidney trans-plantation. Methods Seven kidney transplantation aptionts complicated with pulmonary infection who suffered from high fever, serious dyspnea and was treated with medicines without obvious effect received CRRT therapy for 25 times with BM-25 CRRT machine. Results After the first treatment, the body temperature decreased and symptoms relieved gradually. The 7 patients' condition were much better than before and cured after 2～4 times CRRT and antibiotics therapy. Conclusion CRRT is an effective auxiliary treatment method for serious infection after kidney transplantation. It can relieve patients' symptoms, control high fever, the patients can obtain an opportunity to receive effective antibiotics and other treatment.