Objective To study the influence of the two kinds of dialysis to patients' microinfection, and evaluate the factors associated with microinfection. Methods To explore 46 blood hemodialysis patients, 18 peritoneal dialysis patients and 20 normal controls, plasma CRP, Scr, ALB, SF, Hb, Lp(a) are measured before hemodialysis. CRP is figured as infectional index. Scr、ALB、SF、Hb、Lp(a) are considered as indexes associated with nutrition,anemia and cardiovascular disease．To compare with the infectional indexes between hemodialysis patients and peritoneal dialysis patients．Hemodialysis patients and peritoneal dialysis patients are divided into A (CRP>10mg/L) and B (CRP<10mg/L) themselves. To compare with the factors (Scr、ALB、Lp(a) et) between A and B．Results HD patients' infectional indexes are higher than PD patients',such as CRP（ P<0.05）. The comparitions of associated factors:In HD patients, A' Lp(a) higher than B'（P<0.05）, A' Hb、ALB are lower than B'（P<0.05); A' Scr is lower than B'( P>0.05), A' SF is higher than B'( P>0.05). The comparitions of associated factors:In PD patients, A' Lp(a) is higher than B'（P<0.05）; A' Hb、ALB are lower than B'（P<0.05）; A' Scr and SF are lower than B'( P>0.05). Conclusion HD patients' infection is more serious than PD's, and infection is associate with ALB, Hb, and Lp(a).