PDF(311 KB)

Chinese Journal of Blood Purification ›› 2005, Vol. 4 ›› Issue (8) : 420-423.

论著

Author information +

History +

Abstract

Objective To investigate the effect of Calcitriolum on the influence of parathy-roid (PTH) on residual renal function(RRF). Methods We analyzed the relationship between hormone PTH and calcium(Ca),phosphorus(P)，calcium-phosphorus product (Ca×P), hypertension, triglyceride(TG), cholesterol(CH), left ventricular mass index (LVMI) and glomerular filtration rate (GFR) in 160 hemodialysis patients with chronic renal failure with or without calcitriolum. Results The results showed that 63.6% of the hemodialysis patients with chronic renal failure had secondary hyperparathyroidism(SHPT). We found that PTH had positive correlation with systolic blood pressure (SBP), diastolic blood pressure (DBP), Ca×P, TG and LVMI, and had negative correlation with Ca, GFR, KT/V. GFR had positive correlation with KT/V, and negatire correlation with SBP, DBP, P, Ca×P, TG, CH and LVMI. The levels of PTH, SBP, DBP, P, Ca×P, TG, CH, LVMI were lower and the levels of Ca, GFR were higher in the patients who received Calcitriolum than in the subjects without Calcitriolum. Conclusion Hemodialysisi patients of ten have a high PTH level which could contribute to RRF loss. Calcitriolum can slow down the deterioration of RRF.