Abstract
Objective To study the therapeutic effect of plasma exchange and plasma perfusion（PE+PP）on chronic hepatitis patients with severe jaundice. Methods Seventy-two patients with severe jaundice were divided into two groups randomly. In the treating group, the patients were treated with (PE+PP) on the basis of the conventional therapy, but the control group received the conventional therapy only. The main symptoms, liver function, prothrombin activity(PTA) before and 2 weeks, 4 weeks after treatment, were observed. Results After treating with (PE+PA), the liver function were ameliorated. The prothrombin activity increased significantly. 2 weeks, 4 weeks after treatment, the level of total bilirubin decreased markedly（P＜0.01),the prothrombin activity increased significantly(P＜0.05).The total effective rate in the treating group was 89.2%, while 71.4% in the control group. There were significant differences between the two groups（P ＜0.01). Conclusion Artificial liver support system can ameliorate the liver function of chronic with hepatitis patients severe jaundice. It can also increase the survival rate.
Key words
Chronic hepatitis /
Severe jaundice
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