Abstract
Objective To observe the effect of hemoperfusion and hemodiafiltration in treating uremic perpheral neuropathy. Methods Fourty-five patients with uremic peripheral neuropathy were assigned randomly to hemoperfusion group, hemodiafiltration group and hemodialysis group. Patients of hemodiafiltration group received regular hemodialysis twice a week and hemodiafiltration once a week. The cases of the hemoperfusion group received regular hemodialysis twice a week ahd hemoperfusion once a week. The hemodialysis group received regular hemodialysis thrice a week. The clinical symptoms, the nerve reflex and the sensory conduction velocity(SCV) of median nerve, tibial nerve and lateral popliteal nerve were observed in each group before, 1 month and 2 months cost treatment respectively. Results After treatment, the clinical symptoms,the nerve reflex and the SCV showed no improvement in the hemodialysis group, but significantly improvement in the hemodiafiltration group and hemoperfusion group (P ＜0.05). Conclusion Hemoperfusion and hemodiafiltration are effective for patients with uremic peripheral neuropathy.
Key words
Hemodiafiltration /
Hemodialysis /
Uremic peripheral neuropathy /
Sensory conduction velocity
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