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Chinese Journal of Blood Purification ›› 2007, Vol. 6 ›› Issue (5) : 260-262.

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Abstract

Objectives To observe K+ concentration in dialysate on QT interval and QT scatter degree (QTd) of the patients on maintenance hemodialyis. Methods Sixty cases with chronic renal failure on maintenance hemodialyis were observed, in which dialysates containing 2.0mmol/l and 3.0mmol/l K+ were alternatively used once for a patient. Clinical observation and laboratory examinations were performed. QT interval and QTd from their electrocardiograms were measured after the dialysis for 4 hours. Results After using dialysate containing 2.0mmol/l K+, QT interval and QTd ranged in (595.51±39.01)ms and (63.27 8.46)ms, respectively. When dialysate containing 3.0mmol/l K+ was used, QT interval shortened to (540.61±44.63)ms and QTd to (53.46 8.83)ms. Cardiac arrhythmia was infrequently found in those using 3.0mmol/l K+ in dialysate (P <0.01). When the same K+ concentration in dialysate was used, QTd was greater in patients with pre-dialysis serum K+ <3.5 mmol/l than those with K+ >3.5 mmol/l (P < 0.05). Conclusion Larger QTd reflects the ununiformity and electric instability of ventricular repolarization. Dialysate containing 3.0mmol/l K+ decreases the QT and QTd values and is helpful in the prevention of arrhythmia. Treatment of hypopotassemia before dialysis will reduce the QTd value as well as the risk of arrhythmia during dialysis.