【Abstract】Objective To discuss the method of catheterization and handling process in peroperative period in the uremia patients combined with hepatic cirrhosis and portal hypertension. Methods 6 uremia and hepatic cirrhosis and portal hypertension patients had been involved. They had their catheterization by this sequence in the operation: purse-string suture - discussion of peritoneal cavity - implantation of catheter close peritoneal cavity. After the operations, the input and output volume of peritoneal dialysate had been controlled, and the limits of ascites had been evaluated. Results The loss of ascites in the operation were only 100ml to 600ml in these patients, and their vital sign were stable. Their ascites had been controlled during 5 to 15 days, and no more complication had been found. Conclusion It is feasible for catheterization to uremia patients combined with hepatic cirrhosis and portal hypertension.