【Abstract】Objective To investigate the efficacy and safety of continuous veno-venous hemofiltration (CVVH) in the treatment of pregnancy-induced hypertension complicated with acute left heart failure. Methods Twenty-six pregnancy-induced hypertension patients complicated with acute left heart failure and without improvement after routine therapy were treated with CVVH combined with the routine therapy for at least 2 days. Their clinical manifestations, vital signs, plasma B-type natriuretic peptide (BNP), and ejection fraction (EF) before and after CVVH treatment were compared. Complications during CVVH were also monitored. Results After CVVH, clinical symptoms improved in association with the decrease of heart rate, respiratory rate, blood pressure, central venous pressure and plasma BNP, and the increase of EF and arterial oxygen saturation. Meanwhile, left ventricle end-diastolic diameter (LVEDD) was also improved. No significant complications and acid-base imbalance were found after CVVH. Conclusions CVVH is an effective and safe method for the treatment of pregnancy-induced hypertension complicated with acute left heart failure. It can improve clinical symptoms and heart function in a short period of time without significant complications.