【Abstract】 Objective In order to investigate the determinant factors for bone mineral density (BMD) and the risk factors for osteoporotic fractures in CAPD patients. Methods Eight-four CAPD patients were included in this study. BMD was assessed by dual energy X-ray absorptiometry (DEXA) of lumbar spine and femoral neck. Clinical data and laboratory indices as well as X-ray plain were collected. Results Osteoporosis was found in 11.9% of the 84 patients, and osteopenia in 36.3% patients. Independent variables entering into logistic regression of osteoporosis were sex, age, BMI, Kt/V（P<0.01）and daily urine output (P<0.05). The overall prevalence of fractures since the initiation of peritoneal dialysis was 9.52%. In Cox regression model, fractures were associated with lumbar spine Z-score, femoral neck Z score and BMI. Conclusions Inadequacy of dialysis, low BMI, older age, female and reduced daily urine output may be the important risk factors for osteoporosis in CAPD patients. Lumbar spine and femoral neck Z scores can predict the occurrence of fractures. Among these factors, low BMI is the most important risk factor for fractures in chronic PD patients.