Abstract: 【Abstract】 Objective Patients on continuous ambulatory peritoneal dialysis (CAPD) often have lower quality of life level (QOL) than general population. Malnutrition status and inflammation make important impacts on their morbidity and mortality. However, the factors contributing to the lower QOL remain unclear. This study attempted to assess the correlation of QOL with malnutrition and inflammation. Methods In this cross-sectional study, we collected clinical data, sociodemographic information and laboratory findings from patients' monthly records in this hospital in the period from January to May, 2009. The SF-36 and Subjective Global Assessment (SGA) were used to assess QOL and nutrition status, respectively. Results A total of 212 CAPD patients were enrolled in this study. SGA score was positively correlated with physical functioning (PF), bodily pain (BP), general health (GH), vitality (VT), social function (SF) and mental health (r=0.287, 0.225, 0.344, 0.348, 0.286 and 0.227, respectively; P<0.01). C-reactive protein was negatively correlated with physical functioning (PF), role physical (RP), bodily pain (BP), general health (GH), vitality (VT) and social function (SF) (r=-0.359, -0.178, -0.271, -0.253, -0.236 and -0.198, respectively; P<0.01). Conclusion Malnutrition and inflammation play important roles in QOL. Further studies are necessary to explore the approaches to improve QOL in CAPD patients.

Key words: Dialysis