Abstract: 【Abstract】 Objective To resolve the problems of calcium supplement after parathyroidectomy with forearm autograft in uremic patients. Methodology Fifteen uremic patients who received the operation had their serum concentration of calcium monitored, and the amount of calcium supplement was adjusted based on serum calcium to maintain the serum calcium within the range of 1.8 to 2.5mmol/L. Results The average serum calcium was 2.235±0.082mmol/L within the 2 weeks after the operation. The cumulative amount of calcium supplement within the 2 weeks after the operation (CaSUM) was 48.2±17.9g. To maintain 1mmol/L serum calcium, the average calcium supplement in the 2 weeks after the operation (CaAVG) was 29.1±14.9 mg/day/kg. CaSUM positively correlated to the weight of parathyroid (R=0.910, P=0.038), but did not relate to the duration time of hyperparathyroidism (T), body weight, serum alkaline phosphatase (AKP), normalized protein catabolic rate (nPCR), and the first day serum intact PTH (iPTH) after the operation. CaAVG positively related to the T (R=1, P=0.041), but negatively related to the first day serum iPTH after the operation (R= -1, P=0.002). Conclusion The amount of calcium supplement after parathyroidectomy with forearm autograft correlates to parathyroid weight, the duration time of hyperparathyroidism, and the first day serum iPTH after the operation.

Key words: Uremia, Calcium, Secondary hyperparathyroidism