Abstract: Objective To investigate the effect of evidence-based care on the hemodialysis patients with high arteriovenous fistula vascular access. Method The evidence-based care was performed in 11 hemodialysis patients with brachial artery - cubital vein or brachial artery - high basilic vein arteriovenous fistula vascular access (observation group). We also retrospectively analyzed 11 hemodialysis patients with the implementation of the traditional vascular access care (control group). Results The complications of vascular access was significantly lower in observation group than in control group (P<0.05). Conclusion The evidence-based nursing for the hemodialysis patients with high arteriovenous fistula vascular access facilitates solving the practical problems, so that vascular access complications usually seen in patients with traditional vascular access care are reduced, and the life quality of the patients is improved. This nursing program also promotes the initiative potentials in nurses, enriches their professional knowledge, and enhances their nursing skills for hemodialysis patients.

Key words: Hemodialysis, High arteriovenous fistula