Abstract: 【Abstract】Background The aim of the present study was to analyze the current situation of AKI after cardiac surgery of adults with different age to investigate the possibility of prophylaxis and treatment. Methods We prospectively collected data from patients who underwent cardiac surgery from April 2009 to May 2011 and analyze the incidence and risk factors of AKI after surgery and short-term clinical outcomes of different ages. Results 3896 patients were included. There were 3086 patients in young and middle-aged group(18~65), 772 patients in elderly group(65~80) and 38 patients in senile group(≥80). The male proportion, preoperative serum creatinine, NYHA III grade, preoperative diabetes mellitus, hypertension and coronary angiography, proportion of CABG surgery, proportion of use of adrenaline and noradrenaline for hypotension in elderly group were significantly higher than in young and middle-aged group(all P1.2mg/dl, post-operative use of adrenaline for hypotension were independent risk factors of AKI after cardiac surgery of people over 65years old. Conclusions The AKI incidence after cardiac surgery in elderly people was increased with age and with high mortality. The incidence of AKI was related to a number of perioperative risk factors. Elderly people that occurred AKI after cardiac surgery should also get positive treatment to improve outcomes.

Key words: Cardiac surgery, Elderly people, Acute kidney injury, Hospital mortality, Outcome, Risk factors