Abstract: 【Abstract】Objective To observe valvular calcification (VC) and coronary artery calcification (CAC) in maintenance hemodialysis (MHD) patients, and to explore the possibility of VC for the diagnosis of CAC. Methods Sixty- one MHD patients were enrolled in this study. Serum phosphate, calcium and PTH were measured. Echocardiogram was used to detect VC, and multi-slice spiral CT (MSCT) was performed to assess the score of CAC. Agaston score was used for the estimation of CAC degree. Results ①The median CAC score in non-VC group, one-VC group and two-VC group were 524, 1,006.5 and 2,094.5, respectively. ②Patients’age was older in VC group (73.36±9.28 years) than in non-VC group (61.60±14.87 years). The median CAC score was 1,765 in VC group, and was 524 in non-VC group (P＜0.05). ③ Correlation analysis showed that the level of low density lipoprotein cholesterol was positively correlated with CAC score (r=0.308, P= 0.016). ④Patients with VC had a significantly greater likelihood of having a CAC score ＞1,000 (OR=4.995, 95% CI 0.877～28.445). Conclusion VC and CAC are frequently seen in MHD patients. The presence of VC detected by echocardiogram can predict the degree of CAC.

Key words: coronary artery calcification, valvular calcification, maintein hemodialysis