Abstract: Objective To evaluate nutrition status and its related factors in maintenance hemodialysis (MHD) patients. Method We respectively used modified quantitative subjective global assessment (MQSGA) and body composition monitor (BCM) to evaluate the nutritional status in MHD patients for more than one year. Biochemical markers were collected, and food intake in a period of 3 days was measured by food records. Results We performed an observational study on 87 MHD patients (49 males and 38 females). The prevalence of malnutrition was 32.18% by using MQSGA. The prevalence of malnutrition was 39.08% by using
BCM (lean tissue index <10% of the normal value). There was no difference in evaluating nutrition status between MQSGA and BCM (kappa=0.768). Forty-nine patients had the food intake records, and the average daily protein intake (DPI) was 1.05±0.30 g/(kg· d). According to MQSGA scores, patients were classified into well-nourished group and mal-nourished group. Age, DPI, serum albumin (Alb), serum creatinine (SCr), uricacid (UA), body mass index (BMI), lean tissue index (LTI), and overhydration were significantly different between the two groups (P＜0.05). Logistic analysis revealed that MQSGA score was negatively correlated with Alb(r=-0.38, P=0.001), SCr(r=-0.33, P=0.00), UA(r=-0.32, P=0.01), Kt/V(r=-0.243, P=0.02), BMI (r=-0.338, P=0.001), and LTI (r=-0.471, P= 0.000), and positively correlated with age (r=0.37, P=0.00). In addition, overhydration was independently correlated with age, ALB and BMI (r=0.33, P=0.00) in MHD patients. Conclusions Our data indicate that the assessment of nutritional status by BCM is highly consistent with that by MQSGA. Age, Alb and BMI are the independent factors for malnutrition in MHD patients.

Key words: Nutritional Status, dietary protein intake, hemodialysis