Abstract: Objective To explore the peritoneal non-infection complications in patients with open surgery for catheter implantation and its risk factors. Methods This was a retrospective cohort study. Patients with open surgery for implantation of peritoneal dialysis catheter in our hospital from Jan. 1, 2002 to Jan. 31, 2016 were enrolled in this study. Demographic data, clinical laboratory parameters, catheters, follow-up frequency, non-infection complications due to catheters, treatment, and outcome were collected. Clinical features and the risk factors for the complications were compared between the patients with and without the complications.
Results ①A total of 677 patients were included. The average age was 51.03±12.77 years and the median dialysis vintage was 22 (7.00, 45.00) months. ② Non- infection complications were identified in 125 (18.46%) cases. The most common complication was catheter migration (79 cases, 11.66%), followed by obstruction in catheter, hernia (5.47%), thoracoabdominal fistula (0.74%), and dialysate leakage (0.29%). Regarding outcome of the complications, 109 (87.20% ) patients were cured by conservative treatment, 10 (8.69%) were re-implanted with the catheter, and 6 (5.22%) were transferred to hemodialysis. ③Compared with non-complication group, the patients with complications had a shorter vintage (Z=-14.725, P＜0.001), less follow-up frequency (χ2=7.820, P=0.020), and the operation by less experienced doctors (χ2=9.291, P=0.010). ④Multivariate Cox regression analysis showed that advanced age (HR 1.015, 95% CI 1.01～1.030, P=0.038), less follow-up frequency (HR 1.147, 95% CI 1.010～1.303, P=0.034), and operation by less experienced doctor (HR 1.328, 95% CI 1.096～1.609, P=0.004) were the independent risk factors for non-infectioncomplications after adjustment for confounders. Conclusion The most common non-infection complications were catheter migration and catheter blockage in peritoneal dialysis patients. Most of the patients could be cured by conservative treatment. Advanced age, less follow-up frequency, and operation by less experienced doctors were the independent risk factors for the noninfection complications.

Key words: Peritoneal dialysis, Non-infection complications, Risk factors, open surgery catheter implantation, catheter blockage