Abstract: 【Abstract】Objective To investigate the effect of interdialysis blood pressure on residual renal function(RRF) in hemodialysis patients. Methods A total of 188 patients treated in the Blood Purification Center,The First Affiliated Hospital of Baotou Medical College, Inner Mongolia University of Science & Technology and beginning hemodialysis during the period between Mar. 2013 and Mar. 2017 were recruited. At the 3rd month of hemodialysis, cystatin C (CysC) was assayed and interdialysis blood pressure was measured for one week. Based on the average systolic blood pressure they were divided into group A: <110mmHg, group B:110～160mmhg and group C: >160mmHg; based on the average diastolic blood pressure they were divided into group a: <60mmHg, group b: 60～90mmHg and group c: >90mmHg as well. RRF was compared among different groups, and RRF was calculated from the equation RRF=0.70+22×1/CysC. Results RRF was significantly lower in group A and group C than in group B (P＜0.001), and RRF was lower in group A than in group C, but without statistical difference (P=0.075). Moreover, RRF was significantly lower in group a than in group b and group c (P＜0.001), and was lower in group c than in group b (P＜0.001). Conclusion Maintenance of interdialysis blood pressure in a normal range and prevention of hypertension and hypotension can protect RRF. Lower diastolic blood pressure may accelerate the reduction of residual renal function.

Key words: hemodialysis, residual renal function, blood pressure