Abstract: 【Abstract】Vitamin D deficiency is a common complication in patients with chronic kidney disease(CKD). In uremic patients with maintenance dialysis, vitamin D deficiency rate is as high as 79%. Numerous studies have shown that vitamin D supplementation in CKD patients can treat the abnormal calcium and phosphorus metabolism, prevent secondary hyperparathyroidism, improve bone mineral density, reduce the risk of fractures and reduce the risk of cardiovascular disease. Vitamin D supplementation is also useful for immune regulation, inhibition of inflammatory response, blood pressure control, and reducing urinary protein.

Key words: Chronic Kidney Disease, Active vitamin D, Benefit