Abstract: 【Abstract】Objective To explore the clinical effect of visits by Wechat on anxiety in adult patients with maintenance hemodialysis (MHD). Methods A total of 84 MHD cases from Jan. to Aug., 2016 were recruited as the research subjects. They were divided into experimental group (n=42) and control group (n=42) by using a random number table. Patients in experimental group established a Wechat group to conduct visits by Wechat for 8 months, while patients in control group were treated with routine health care. Results Anxiety in patients in experimental group alleviated after the intervention. Compared with control group, the self-rating anxiety scale (SAS) scores were statistically better in experimental group (46.79±6.09 vs. 59.55±4.74, t=10.710, P＜0.001); the cognitive level of the disease was statistically higher in experimental group (χ²=10.918,P =0.001； χ²=7.941，P =0.005； χ²=7.375，P =0.007； χ²=9.143，P =0.002； χ²=13.123，P ＜0.001； χ²=15.774，P ＜0.001； χ²=6.943，P ＜0.008); blood urea nitrogen (BUN) index (9.01 ± 3.33 vs.18.01±2.68, t=5.399, P=0.021), serum creatinine (Scr) index (336.45±82.31 vs. 426.45±70.26, t=3.984, P=0.026) and β2-microglobulin (β2-MG) index (14.81±1.35 vs. 17.23±3.12, t=3.612, P=0.030) were statistically lower in experimental group. Conclusion Through visits by Wechat, the anxiety in adult MHD patients improved, and the cognitive level of the disease enhanced. The therapeutic effect and the quality of life improved as well.

Key words:  Visit by WeChat, Adult, Hemodialysis, Anxiety