Abstract: 【Abstract】Objective To analyze the prevalence of low serum intact parathyroid hormone (iPTH) level and to evaluate the risk factors for the low serum iPTH in patients on continuous ambulatory peritoneal dialysis (CAPD). Methods Patients with regular CAPD and followed up for more than 3 months in the Department of Nephrology, Beijing Luhe Hospital from January to December 2016 were enrolled in this study. They were retrieved from the Huibaitong medical database. Their general condition and follow-up information were recorded and analyzed. Results A total of 133 CAPD patients were included in this study. Their average age was (62.50±13.33) years. The prevalence of hypoparathyroidemia was 56.39% in these patients. Their average dialysis duration was 26.37 (13.39, 44.88) months. Age (Z=2.707, P=0.007), diabetes (χ2=8.512, P=0.004), serum calcium (Z=2.588, P=0.010), random blood glucose (Z=2.760, P=0.006) and carbon dioxide level (t=2.667, P=0.008) were significantly higher in hypoparathyroidemia patients than in non-hypoparathyroidemia
patients; dialysis duration (χ2=2.419, P=0.032), serum phosphorus (t=3.914, P＜0.001), serum creatinine (t=3.272, P=0.001), serum albumin (Z=2.485, P=0.013) and geriatric nutritional risk index (Z=2.451, P=0.014) were significantly lower in hypoparathyroidemia patients than in non-hypoparathyroidemia patients. Logistic regression showed that higher serum calcium was the independent risk factor for hypoparathyroidemia (OR=145.062, 95% CI 9.957～2113.463, P＜0.001). Conclusions The prevalence of hypoparathyroidemia was higher in CAPD patients. Diabetic patients were more susceptible to have hypoparathyroidemia. Higher serum calcium was the independent risk factor for hypoparathyroidemia.

Key words: Peritoneal dialysis, Parathyroid hormone, Renal osteopathy, Malnutrition, Regression analysis