Abstract: 【Abstract】Objective To explore the relationship between red blood cell distribution width (RDW) and intradialytic hypotension (IDH). Methods A total of 238 cases of maintenance hemodialysis patients treated in the hemodialysis center of our hospital during January 1st, 2017～June 1st, 2018 were recruited as research subjects. According to the presence or absence of IDH, they were divided into observation group (50 cases) and control group (188 cases). IDH and RDW were recorded in the two groups. Independent sample t test was used to investigate the relationship between IDH and RDW, hemoglobin, age, gender, total cholesterol, low density lipoprotein (LDL), phosphorus, calcium, parathyroid hormone, etc. Multivariate logistic regression was used to analyze the independent influence factors for IDH. The receiver operating characteristic curve (ROC curve) was obtained to evaluate the diagnostic value of RDW for IDH. P<0.05 was considered to be statistically significant. Results There were significant differences in gender (t=10.024, P=0.002), age (t=4.875, P=0.000), RDW (t=5.673, P=0.000), total cholesterol (t=3.065, P=0.002) and LDL (t=2.787, P=0.006) between the two groups. After correction of IDH, RDW became lower but still had statistically significance (t=5.805, P＜0.001). The ROC curve showed that RDW had a predictive effect for IDH (AUC=0.869, 95% CI 0.791～0.926, OR=1.249). Conclusions The increase of RDW is an important risk factor as well as a better predictive index for IDH.

Key words: Red blood cell distribution width, hypotension, hemodialysis