Abstract: 【Abstract】Objective To investigate the prevalence of anxiety and depression and their effects on quality of life in maintenance hemodialysis (MHD) patients. Methods MHD patients treated in the Dialysis Unit of Sichuan Provincial Ziyang People’s Hospital from Jan. 2017 to Dec. 2017 were enrolled in this cross-sectional study. Self-rating Depression Scale (SDS), Self-rating Anxiety Scale (SAS) and KDQOL-SFTM Questionnaire were used to assess anxiety, depression and quality of life in MHD patients. Results ①A total of 124 MHD patients were enrolled in this study. The prevalence of anxiety, depression and comorbid depression and anxiety were 16.13%, 36.29% and 10.48% respectively. ②The MHD patients without anxiety/depression had better performance than those with anxiety/depression (P<0.05), and those with comorbid depression and anxiety had lower performance than those without anxiety, depression or comorbid depression and anxiety. ③The scores of SAS and SDS were negative correlated with KDTA score and SF-36 score (P＜0.05). Conclusion The prevalence of anxiety, depression and comorbid anxiety and depression were 16.13%, 36.29% and 10.48% respectively in the MHD patients treated in the hemodialysis center of Sichuan Provincial Ziyang People’s Hospital. Anxiety and depression impair the quality of life in MHD patients, especially in those with comorbid anxiety and depression.

Key words: Maintenance hemodialysis, Anxiety, Depression, quality of life