Abstract: 【Abstract】Objective To explore the clinical features and possible etiology of acute pancreatitis in maintenance hemodialysis (MHD) patients. Method A total of 125 MHD patients in our dialysis center from July 2017 to September 2018 were enrolled in this study and divided into pancreatitis group and control group. The clinical manifestations and biochemical examination results of the patients in pancreatitis group were analyzed. Results Five MHD cases (4%) with acute pancreatitis are analyzed. The main clinical manifestations are abdominal pain and vomiting. As compared with the control group, patients in pancreatitis group have significantly higher levels of serum calcium (2.52±0.07mmol/L vs. 2.13±0.03mmol/L, t=3.534, P＜0.001), fasting blood glucose (12.93±1.96mmol/L vs. 8.37±0.36mmol/L, t=2.529, P=0.013) and hemoglobin (123.80±7.77g/L vs. 113.26±1.15g/L, t=2.197, P=0.028). There are no significant differences in age, kt/v, serum albumin, serum creatinine, serum phosphorus, serum cholesterol, serum triglycerides, serum parathyroid hormone, left ventricular ejection fraction and average between the two groups. Conclusion Higher levels of serum calcium, fasting blood glucose and hemoglobin may be responsible for the complication of acute pancreatitis in MHD patients. Continuous blood purification treatment is effective in severe acute pancreatitis.

Key words: Hemodialysis, Pancreatitis, blood purification, Calcium