Abstract: 【Abstract】Objective To explore the application value of closed loop management of Internet of Things in disposal of medical waste of peritoneal dialysis (PD) patients at home. Methods A total of 119 PD patients at home were randomly divided into control group (n=61) and intervention group (n=58). Conventional education and guidance were given to the control group, and closed loop management of Internet of Things in addition to the conventional education and guidance were given to the intervention group. The self-designed questionnaire was used to understand the disposal of medical waste by PD patients. The disposal of medical waste before and after the intervention was compared between the two groups. Results In the intervention group, the rate of standardized disposal of medical waste increased from 3.4% before the intervention to 91.4% after the intervention (χ2= 89.327, P<0.001), and the rate of standardized disposal of medical waste was significantly higher in the intervention group than in the control group (χ2=82.338, P<0.001). The recovery rate of PD waste liquid bags in the intervention group increased from 3.47% before intervention to 91.37% after intervention (χ2=86.726, P<0.001). The recovery rate of PD waste liquid bags was significantly higher in the intervention group than in the control group (χ2=76.842, P<0.001). Conclusion The closed loop management of Internet of Things can standardize the behavior of disposal of medical waste in PD patients at home. This method
is valuable for practical use, and is the recent trend of medical waste management for PD at home.

Key words: Internet of Things, Closed loop management, Peritoneal dialysis, Medical waste