Abstract: Objective   To explore the effects of core stabilization training on exercise ability, dialysis adequacy, fatigue symptoms and quality of life in patients with maintenance hemodialysis (MHD).   Methods  Sixty patients undergoing MHD in the Hemodialysis Center of The Sixth People's Hospital Affiliated to Shanghai Jiao Tong University School of Medicine from November 2023 to May 2024 were selected as the study objects. They were divided into the experimental group (29 cases) and the control group (31 cases) by random number table method. The control group received conventional treatment and nursing, and the experimental group received core stabilization training on the basis of conventional treatment and nursing. The differences of urea clearance index (Kt/V ), urea reduction rate (URR), 30 second sit to stand test (30s STS), 6-minute walk test (6MWT), fatigue scale-14 (FS-14) scores, and the 36 item short form health survey (SF-36) scores were compared between the two groups before and after the intervention.  Results   After core stability training, the scores of Kt/V, URR, 6MWT, 30s-STS, FS-14, and SF-36 in the experimental group were significantly different from the baseline levels (t =- 6.558, 5.289, -14.028, -25.713, -3.251 and -12.371 respectively; all P＜0.001) and significantly different from those in the control group (t =7.271, 2.758, 7.072, 11.905, -5.647 and 3.276 respectively; P＜0.001, 0.021, ＜ 0.001, ＜ 0.001, ＜ 0.001 and 0.002 respectively).  Conclusions   Core stabilization training during dialysis can improve dialysis adequacy, enhance exercise ability, reduce fatigue symptoms, and improve quality of life in MHD patients.

Key words: Maintenance hemodialysis, Core stability training, Dialysis adequacy, Athletic ability, Fatigue, Quality of life