Abstract: Objective To explore the trajectory change of volume load management, and to discuss the correlation between different trajectories and physical activity in peritoneal dialysis (PD) patients. Methods A total of 155 patients undergoing PD were selected by convenience sampling. A questionnaire was used to conduct surveys on them within one week of the initial dialysis (T1), and after regular dialysis for one month (T2), 3 months (T3), and 6 months (T4). Result Three volume load management trajectories were identified, namely the low-level upward group (C1, n=50), the medium-level upward group (C2, n=56), and the low-tomedium-level fluctuation group (C3, n=41). There were significant differences among the 3 trajectory categories in terms of educational level (χ2 =13.570, P=0.035), diabetic nephropathy (χ2 =11.640, P=0.003), concurrent peritonitis during the period (χ2 =18.677, P＜0.001), and hypoproteinemia (χ2 =6.947, P=0.031). Within the initial 6 months of PD (T1-T4), physical activity scores of the patients showed an upward trend in every group (C1: F=109.134, P＜0.001; C2: F=46.537, P＜0.001; C3: F=33.361, P＜0.001); during T1-T4 stages, there were significant differences in distribution of physical activity scores among the three groups (T1: F= 5.364, P=0.005; T2: F=9.015, P＜0.01; T3: F=27.156, P＜0.001; T4: F=40.333, P＜0.001). Conclusion Educational level, diabetic nephropathy, concurrent peritonitis and hypoproteinemia have impacts on trajectory change of volume load management in PD patients. Moreover, volume load management at different stages have impacts on physical activity of the patients.

Key words: Peritoneal dialysis, Capacity load, Capacity management, Physical activity