Abstract: Objective  To identify the inflection point age of life space constriction in elderly maintenance hemodialysis (MHD) patients and to explore its influencing factors.  Methods  A total of 412 elderly MHD patients treated in the Hemodialysis Centers of Kunshan First People's Hospital, Kunshan Hospital of Traditional Chinese Medicine and Kunshan Third People's Hospital from November 2024 to June 2025 and selected by convenience sample method were enrolled as the research subjects. Receiver operating characteristic (ROC) curve was used to determine the inflection point age of life space constriction. Additionally, the effects of general demographic data and disease-related information on life space constriction in these patients were analyzed.  Results  The prevalence of life space constriction among elderly MHD patients was 49.03%. ROC curve analysis revealed that age had a high predictive value for life space constriction, with an area under the curve (AUC) of 0.966 (95% CI: 0.949～0.982). The overall inflection point age for life space constriction in this population was 68.5 years. Influencing factors included advanced age (OR=1.429, 95% CI: 1.236～1.653, P＜0.001), type of vascular access (OR=5.190, 95% CI: 1.389～19.394, P=0.014), sedentary behavior (OR=4.784, 95% CI: 1.265～18.097, P=0.021), post-dialysis fatigue (OR=1.123, 95% CI: 1.051～1.201, P＜0.001), learned helplessness (OR=1.122, 95% CI: 1.057～1.191, P＜0.001), sarcopenia (OR=10.081, 95% CI: 0.015～0.436, P=0.003), and fall down efficacy (OR=0.944, 95% CI: 0.905～0.984, P=0.007).   Conclusion   Age is a strong predictor of life space constriction in elderly MHD patients. Special attention should be paid to elderly MHD patients with advanced age, central venous catheter placement, sedentary behavior, post-dialysis fatigue, learned helplessness, sarcopenia, and fall down efficacy.

Key words: Elderly, Maintenance hemodialysis, Life space, Influencing factor