Abstract: Objective To evaluate the prevalence of insomnia in our hemodialysis center and to analysis the influencing factors of insomnia. Methods Sixty-seven patients on maintenance hemodialysis were involved in this study. Insomnia, excessive daytime sleepiness(EDS), restless leg syndrome(RLS), sleep quality were diagnosed by the Athens Insomnia Scale(AIS), Epworth Sleepiness Scale(ESS), the criteria of the International Restless Legs Syndrome Study Group(IRLSSG), Pittsburgh Sleep Quality Index(PSQI) respectively. General state(gender, high blood pressure, diabetes, rejection after renal trans-plantation, smoking, drinking tea, RLS, EDS), dialysis data( age, duration of HD, dry weight, body mass index, times of HD weekly), biochemical parameters (serum creatinine, blood urea nitrogen, Kt/V, hemoglobin, haematocrit, ferritin, transferring saturation, potassium, calcium, phosphorus, intact parathyroid hormone, albumin, C-reactive protein) were collected at the same time. We divided our population into two groups: with insomnia (AIS score=6) and without insomnia (AIS score<6). Statistical analyses were made between the two groups. Results ①The questionnaire revealed the presence of insomnia (38.81%). ②The scores of seven components in the PSQI of insomnia group were higher than those of another group(P<0.05）.③There were significant differences in RLS, age and ferritin (P<0.05)between two groups. ④ Binary Logistic Regression analysis showed that RLS and age significantly influenced insomnia(P<0.05). The odds ratios were 24.451 and 1.078 respectively. Conclusion The prevalence of insomnia of maintenance hemodialysis patients from our center was 38.81%. Patients with insomnia also suffered from poor sleep quality, mainly in subjective sleep quality, sleep duration, habitual sleep efficiency, daytime dysfunction. RLS and age were risk factors of insomnia. The lack of ferrum and/or some middle molecules that can not be eliminated might influence sleep.

Key words: Hemodialysis, Restless leg syndrome, Age