Abstract: 【Abstract】 Objective To compared dialysis adequacy, catheter function and complications among hemodialysis patients using the new type long-term dialysis catheter of Palindrome, those using permcath long-term dialysis catheter, and those using arteriovenous fistulas as the vascular access. Methods A total of 43 cases using Permcath long-term dialysis catheter with complete clinical data was assigned as Permcath group, 49 cases using Palindrome catheter with complete clinical data as Palindrome group, and 56 cases using arteriovenous fistula (AVF) with complete clinical data as AVF group. Their urea clearance (Kt/V), urea reduction rate (URR), the largest blood flow, catheter-related infection, catheter thrombosis formation, and the patency rate in a year were observed.  Results The maximum blood flow velocity was significantly higher in Palindrome group than in Permcath group. The rate of patients using long-term dialysis catheters as blood access was finally 49.2%, but was only 17.4% at the earlier dialysis course. Secondary kidney damages (metabolic disease, hypertension, ischemic nephropathy, etc.) accounted for 73.1% patients to use long-term dialysis catheters, and only 51.5% patients to use AVF (t= 13.064, P=0.000). Kt/V, URR and the catheter patency rate in a year were better in Palindrome group than in Permcath group (P=0.02, 0.007, 0.021, respectively), but were similar between Palindrome group and AVF group. Blood access related infection was higher in Palindrome group than in AVF group (χ2=4.5946, P=0.032). The prevalence of thrombosis was 30.6% in Palindrome group, lower than that in Permcath group (48.8%, χ2=7.8125, P=0.005), and higher than that in AVF group (5.4%, χ2=5.9019, P=0.015).  Conclusion The effects of long-term Palindrome dialysis catheter on maximum blood flow, dialysis adequacy and one year patency rate were superior to Permcath catheter, and were similar to AVF. However, Palindrome catheter had higher prevalence of infection and thrombosis. Therefore, long-term Palindrome dialysis catheter can be used as the better complement but not the best approach for blood access in patients on maintenance hemodialysis.

Key words: Long-term dialysis catheter, ,Palindrome,Arteriovenous fistula,Dialysis adequacy,Complication