Abstract: 【Abstract】 Objective: To investigate the health- related quality of life in patients with chronic kidney disease(CKD), and analysis the possible relating factors of this disease. Methods：The Chinese version of the EuroQol Group’s 5-domain 3 level questionnaire(EQ-5D-3L) was used to interview the CKD patients. At the same time we collected the general messages and clinical laboratory testing results of these patients, then found out the factors that affected the quality of life in patients with CKD using correlation analysis. Results: The visual analogue scale(VAS) scores were consistent with the health description system evaluation results. The VAS scores were negative related to age, Scr, BUN, CysC, p, Ca•P, ferritin and Up/Ucr, while had a positive correlation with eGFR, Hb, Alb and ApoA1. Conclusion: The survey in our center showed that female patients of CKD were more prone to anxiety and depression status. The renal function, anemia and micro inflammation state had significant influence to the quality of patients’ life, which verified that this simple and feasible scale can reflect the health related quality of life of CKD patients in a good way.

Key words: EQ-5D-3L, Chronic kidney diseases, Health related quality of life